![]() There was a shorter median time to discharge of 51 h (19–432 h) in patients given antivenom 4 h. Early antivenom administration was associated with a decreased frequency of neurotoxicity, acute kidney injury, myotoxicity and intubation. A greater total antivenom dose was associated with VICC, neurotoxicity and acute kidney injury. ![]() Antivenom was given to 34 patients with a median initial dose of one vial (range 1–4), and a median total dose of two vials (range 1–9). Venom allergy occurred in seven patients, three of which had no evidence of envenoming and one died. Systemic envenoming occurred in 33 patients with neurotoxicity (26), complete venom induced consumption coagulopathy (VICC) (16), partial VICC (15), acute kidney injury (13), myotoxicity (11) and thrombocytopenia (7). Results: There were 40 confirmed taipan bites: median age 41 years (2–85 years), 34 were males and 21 were snake handlers. Blood samples were taken and analysed by venom specific immunoassay to confirm snake species and measure venom concentration pre- and post-antivenom. Data were collected prospectively on all snakebites, including patient demographics, bite circumstances, clinical effects, laboratory results, complications and treatment. Methods: Confirmed taipan bites were recruited from the Australian Snakebite Project. The objective of this study was to describe taipan envenoming in Australian and its response to antivenom. Context: Taipans (Oxyuranus spp.) are medically important venomous snakes from Australia and Papua New Guinea.
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